Decoding the Language of Cells. Designing Better Therapies.
QMI reveals real-time signaling networks driving efficacy, safety, and persistence.
Quantify the protein networks driving CAR-T function
Standard assays blur the signaling picture. QMI delivers clear, multiplexed readouts of intracellular protein interactions — revealing how your CAR constructs activate, persist, or fail before they reach the clinic.
Why QMI?
Unlike traditional proteomics, which measures abundance, QMI (Quantitative Multiplex Immunocoprecipitation) measures function — revealing how proteins assemble into active complexes that determine fate decisions like T cell activation, exhaustion, and persistence.
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Standard assays fall short
Flow cytometry, cytokine release, and killing assays can’t predict how CAR-T constructs will behave in humans.
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QMI maps real-time protein networks
We measure downstream protein-protein interactions in real time — identifying signaling hubs that drive activation, persistence, or exhaustion.
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Predict efficacy before the clinic
QMI helps you catch failures early, compare construct variants, and select designs with the highest potential to succeed in patients.
Our Services
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Run QMI on your CAR-T constructs to map intracellular signaling in human T cells.
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Test the functional impact of hinge, linker, transmembrane, or co-stimulatory domain swaps.
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Detect early signals of overactivation, tonic signaling, or exhaustion before clinical trials.
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We design custom QMI panels for any protein interaction system and work with translational teams to link protein networks to patient outcomes.
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Consult our experts.
Contact us.
Our Work
